Acupuncture has proven effective in relieving nausea associated with chemotherapy for some cancer patients.
As more and more cancer patients rely on complementary therapies to help them manage their disease, the question inevitably arises as to the appropriateness of such practices. The number of integrative modalities available to patients today is mind-numbing – ranging from energetic healing to Chinese herbal preparations. Yet despite the almost infinite array of offerings, there are some basic rules that can help keep cancer patients safe while exploring forms of healing that transcend western medicine.
Rule #1: Integrative treatments are no substitute for proven medical interventions that control or cure cancer. This first rule is inviolate – consider it the one red-line that you should never cross. Therefore, you can eliminate the thought of “alternative” medicine, and replace it with integrative or complementary medicine.
Complementary therapies do not replace or supplant traditional methods of managing cancer. Rather, they are intended to provide additional benefits to the cancer patient, which may vary from reducing the adverse side effects of treatment to attempting to bolster the patient’s immune response. They are thus intended to complement standard oncology practices.
The term alternative therapies suggest that these interventions are done in lieu of medical treatment—an obviously risky decision, particularly if there are effective treatment modalities available for your cancer. Yet, even some of the brightest people on the planet have chosen to forgo standard medical therapy in pursuit of alternative treatment:
“Giving up conventional medicine in favour of alternative treatments, tops the list of fatefully wrong decisions. Whenever this has hastened the death of a famous individual, like recently Steve Jobs, the world press briefly takes notice only to revert to ‘business as usual’ a few days later. And ‘business as usual’ means all too often the promotion of quackery to desperate patients. Thankfully, most cancer patients do not abandon conventional oncology but use alternative treatments as an adjunct to it.”[i]
One of the preeminent experts on complementary medicine, Barrie Cassileth, PhD, is crystal-clear in her opinion regarding the role of alternative medicine in cancer care—there is none! Dr. Cassileth, who is the founder of Memorial Sloan-Kettering’s integrative medicine program, offered these thoughts in an interview with Medscape journalist Gabriel Miller:
“The most common misconception and misperception is that there is a relationship between alternative therapies and complementary therapies, which are part of integrative medicine. There are no viable alternatives to mainstream cancer care, but there are many products and services that are sold to the public, to the naive public, calling themselves alternative medicines or alternative therapies….All of this is bogus. There are no viable alternatives to mainstream care, but a lot of people are getting wealthy pushing alternatives. In other words, they say, “Don’t bother with mainstream treatment; you don’t have to get surgery or chemotherapy or whatever. Come here, and we will treat you.” With something that turns out to be utter nonsense. What happens to these patients…they usually die because they failed to get treatment when it was needed. That is alternative medicine. No one who is a reliable person at a reliable institution would have anything to do with alternative medicine, also called quackery.”[ii]
Most physicians would agree with Dr. Cassileth…so don’t expect your doctor to turn cartwheels if you elect to forgo traditional medical care in favor of alternative medicine. It should be noted that, despite the significant difference between complementary and alternative medicine, they are often spoken of together as differing from traditional or allopathic medicine.
Rule #2: Complementary treatments should be evaluated relative to their ability to improve quality of life – not eliminate or control disease. Significant research data supports the assertion that certain complementary modalities appear to have a profoundly positive effective on selective measures of quality of life (QoL).
he degree to which complementary therapies are effective depends upon one’s expectations relative to treatment outcomes. If you are engaging in such therapies in an effort to ameliorate tumors that are resistant to standard medical therapies, chances are you will be disappointed by the outcome. However, if your expectations are more modest and focus primarily on improved quality of life, complementary therapies may prove to be of significant value to you. Since quality of life can affect clinical outcomes over time, the value of complementary therapies may be substantial:
- “The efficacy of some complementary therapies for cancer treatment and palliation has been documented. Chinese herbal medications are associated with reduced treatment adverse effects, increased quality of life, and improved survival rates across cancer sites. Estrogenic botanical supplements have been associated with better quality of life in patients with breast cancer. Massage therapy has been shown to reduce lymphedema in breast and gynecologic cancers, and decrease pain and improve mood in patients with advanced cancers. Randomized trials have shown acupuncture reduces the number and severity of hot flashes in women with breast cancer and men with prostate cancer.”[iii]
- “Studies have found acupuncture to be useful in managing chemotherapy-associated vomiting in some cancer patients. Although research on acupuncture for cancer pain control and for management of other cancer symptoms is limited, some studies have shown beneficial effects that warrant further investigation. A 2008 evidence-based review of clinical options for managing nausea and vomiting in cancer patients noted electroacupuncture as an option to be considered.”[iv]
- “Various studies also suggest possible benefits of complementary therapies such as hypnosis, massage, meditation, and yoga in helping cancer patients manage side effects and symptoms of the disease. For example, a study of 380 patients with advanced cancer concluded that massage therapy may offer some immediate relief for these patients, and that simple touch therapy (placing both hands on specific body sites)—which can be provided by family members and volunteers—may also be helpful. The study was conducted at 15 hospices in the Population-based Palliative Care Research Network.”[v]
- “A 2008 review of the research literature on botanicals and cancer concluded that although several botanicals have shown promise for managing side effects and symptoms such as nausea and vomiting, pain, fatigue, and insomnia, the scientific evidence is limited (the reviewers did not find sufficient evidence to recommend any specific treatment), and many clinical trials have not been well designed. As with use for cancer treatment, use of botanicals for symptom management raises concerns about interactions with cancer drugs, other drugs, and other botanicals”.[vi]
Clearly, a significant level of research exists demonstrating the effectiveness of selective complementary therapies within the appropriate context. Before engaging in complementary therapies, however, you need to also understand the potential dangers associated with them.
Rule #3: Do not ingest anything without discussing it first with your physicians. You probably won’t get into too much trouble with non-invasive modalities such as acupuncture, massage therapy, aromatherapy…but ingesting unknown substances is a wholly different matter.
CAM therapies are often marketed as “natural alternatives” to medicine—leading some patients to believe that they are without risks. While prayer, meditation, massage, and other forms of therapy that do not involve the ingestion of any type of compound are generally devoid of risk, other therapies cannot make this claim.
Mary Egger, RN, advises patients, “If it is something that they ingest, they need to check with the doctors first because it could be counter-productive to treatment.” There are three principal dangers when ingesting a diverse range of CAM therapies: 1) There can be a direct reaction to the compounds; 2) the compounds can negatively interact with chemotherapy, radiation therapy, or other medicines; 3) the CAM compounds/herbals can be contaminated.
CAM products can be very biologically active. In other words, “Direct adverse effects such as allergic reactions, gastro-intestinal complaints, photosensitivity, skin reactions, and hepatotoxicity [toxic and potentially damaging to the liver] have been reported as side effects to CAM commonly used by cancer patients. For example, Echinacea, used to bolster immunity, has caused allergic reactions including anaphylaxis; St. John’s wort, used to treat depression, may cause photosensitivity; black cohosh, used to improve menopausal symptoms, may cause gastrointestinal upset and hepatotoxicity.”[vii]
As more and more cancer patients turn to CAM, the number of adverse reactions increases proportionately:
“Side effects and interactions with chemotherapy are being increasingly reported with herb use, and concerns about potential interactions of complementary modalities with biomedical and pharmacologic treatment, safety, efficacy, cost, and establishment of scientific evidence are rising. Given that many botanical supplements lack basic and clinical research documentation and are not closely regulated, many supplements may be contaminated. Toxicity may result from high concentrations of active ingredients in a supplement versus the native form of the natural product. Moreover, there remains a lack of reliable dosage guidelines. Nearly two thirds of individuals reporting use of natural supplements are unaware of drug interactions and information concerning adverse effects, making the assumption that a lack of such information implies safety. Studies on the effects of antioxidants on cancer therapies have yielded mixed results, with some reporting interference, others noting benefits, and most suggesting no significant interaction. Still, caution is recommended for people undergoing treatment with chemotherapy or radiation because it has been proposed that the use of high-dose antioxidants may interfere with the effectiveness of treatment.”[viii]
If you think these CAM-drug interactions are rare, you are wrong. Researchers state that more than 25% of cancer patients who are receiving chemotherapy are likely at risk for a significant adverse reaction.[ix]
Lori Lindstrom, M.D. notes: “When I initially review a patient’s medication list, I first make sure they have listed all prescription and non-prescription medications, as well as vitamins, herbs, and supplements. The fish oil they take may be dangerous because it increases their risk of bleeding; the anti-oxidant Vitamin C can potentially interfere with the intended effects of radiation. The soybean estrogen may stimulate their breast cancer to grow. In all of these situations, seemingly innocuous supplements can potentially cause harm. My best advice is to not to take any supplement, unless you absolutely need it, while undergoing cancer therapies.”
As if these dangers were not enough, there are also safety concerns related to the manufacturing processes for CAM products. Many herbal preparations are manufactured in foreign countries with far less stringent manufacturing standards to protect product safety and purity. As a result, so-called all natural products may be contaminated with lead, cadmium, arsenic, or other toxins. Even in the United States, oversight of CAM products pales compared to the scrutiny applied to traditional pharmaceutical manufacturing.
The sheer number of herbal remedies marketed makes the challenge of validating their effectiveness, purity, and safety almost Herculean. Dr. Edzard Ernst, emeritus professor at the University of Exeter, makes this point abundantly clear:
“There are about 6,000—that is a really rough estimate—different herbal remedies, and each of them has its own dangers, its own risks. But generally speaking, the risks are, of course, toxicity of the herb itself, and then interactions with prescribed drugs. Here we only know the tip of the iceberg because research into this area has only just begun. We know that herbs have the potential to interact, but we don’t know enough about the subject. If we are dealing with Asian herbal mixtures in particular, we know that many of them are contaminated and/or adulterated—adulterated with prescription drugs and contaminated, for instance, with heavy metals, which obviously can cause harm. The biggest danger of all is that these supplements might be used as a true alternative to effective treatments. In this situation, a harmless but ineffective remedy can almost immediately become life-threatening.”[x]
Rule #4: Just as you were discerning about your medical doctor, be equally discerning when selecting an integrative provider. There are legitimate, certifying organizations that convey Board certification or comparable credentials to acupuncturists, massage therapists, Chinese medicine practitioners, and others within this field. However, there are also charlatans!
I have attended meetings where the virtues of miracle cures were peddled to unsuspecting patients with merciless conviction. And when I challenged these hucksters—demanding valid proof of their claims, I was routed out of the audience with great haste. In one case, a death threat followed.
What I found most surprising was the degree to which intelligent, rational individuals were buying into this nonsense. It spoke volumes about their extreme vulnerability and desperate need for hope.
If you think you are immune to the “charms” of a quack, think again. Even the most astute, well-educated patients have fallen prey: “Psychopathic traits of superficial charm and pathological lying, when exhibited by a quack practitioner giving cancer patients the very words they want to hear such as “cancer cure,” can lead the vulnerable patient into their grasp.”[xi]
Rule #5: Begin by Seeking Out Trustworthy Information
Sources of trustworthy information
Complementary therapies can have a profoundly positive impact on cancer patients when expectations are appropriate and the therapies are properly utilized. There are numerous sources of trusted information that you may wish to consider before engaging in complementary therapies, including:
- The American Cancer Society: http://www.cancer.org/treatment/treatmentsandsideeffects/complementaryandalternativemedicine/index
- National Cancer Institute’s Office of Cancer Complementary and Alternative Medicine (OCCAM): http://cam.cancer.gov/cam/
- National Institute of Health’s National Center for Complementary and Alternative Medicine (NCCAM): http://nccam.nih.gov/
Your Next Step: Discussing complementary and alternative therapies with your physician
It’s important that you feel comfortable discussing complementary medicine with your physicians. Research indicates that “the majority of CAM use is not being communicated to providers.”[xii] Since we have seen how certain CAM therapies can interact with traditional treatment modalities or cause harm in other ways, this reluctance to share such information with your physicians must be overcome.
IF YOU ARE INTERESTED IN MORE INFORMATION ON THIS TOPIC, YOU MAY WISH TO READ:
After You Hear It’s Cancer: A Guide to Navigating the Difficult Journey Ahead,Rowman & Littlefield, Publisher. Here is a link to the book on Amazon.com.
[i] Edzard Ernst, “Alternative Treatments for Breast Cancer,” European Journal of Clinical Pharmacology 68 (2012): 453, http://paperity.org/p/19734319/alternative-treatments-for-breast-cancer.
[ii] Gabriel Miller, Barrie R. Cassileth, and Edzard Ernst, “Asking the Experts: Complementary and Alternative Medicine and Cancer,” Medscape, September 2, 2014, http://www.medscape.com/viewarticle/830553_print.
[iii] Perlman et al., “Prevalence and Correlates,” 34.
[iv] National Center for Complementary and Alternative Medicine, “Cancer and CAM: What the Science Says,” NCCAM Clinical Digest (October 2010).
[vii] Smith et al., “Why Do Some Cancer Patients,” 3.
[viii] Anderson and Gill, “Use of Complementary Therapies,” 239.
[ix] Smith et al., “Why Do Some Cancer Patients,” 4.
[x] Miller et al., “Asking the Experts.”
[xi] Smith et al., “Why Do Some Cancer Patients,” 3.
[xii] Mao et al., “Complementary,” 12.